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As you age, the number of fibroblasts in your skin reduces and the production of new Extracellular Matrix (ECM) slows down as well. Restoration of the intake of nutrients for fibroblasts happens through ECM targeting. ECM targeting also stimulates the production of hyaluronic acid, collagen fibers and elastic fibers, including type IV collagen. 

SUNEKOS® is a unique skin booster from Italy made up of Hyaluronic Acid & patented specific mix of 6 Amino Acids (i.e. Glycine, L- Proline, L- Alanine, L- Leucine, L- Valine, and L- Lysine). It  promotes extracellular matrix (ECM) regeneration for dermal tissues by stimulating fibroblast activities and collagen stimulation. Sunekos’ patented formula of Amino Acids is precisely balanced to assure the production of new collagen and new elastin.

SUNEKOS® utilises Amino Acid’s biological diversity and synergy, in combination with Hyaluronic Acid, to restore skin’s health and physiological balance. Not only does it provides hydration, it gives a volumising effect. It stimulates the production of collagen and elastin naturally, helping the production of new ECM for skin elasticity. The filler even boosts production of Type 4 collagen, which is the hardest type of collagen to reproduce.

The SUNEKOS® treatment is effective in lightening dark eye circles, reducing the overall appearance of wrinkles and providing volume to crepey skin, as well as sunken facial features. The treatment also helps to hydrate the treated tissues.

It can be used on any kind of dermis and in different parts of the body as: face, neck, décolleté and hands. It is particularly effective in the periocular area, to reduce dark circles and bags, and also on the forehead area. 

Due to its characteristics and through a specific injection technique, it is recommended to obtain lifting effect or volumizing effect.

In addition, Sunekos® can be combined with other treatments too. In fact, it complements energy-based treatment such as Ultherapy or HIFU for more visible skin tightening and face lifting. 

It can be also be combined with BTX and fillers for age-related wrinkling and hollowing to replace volume loss and soften lines.

A Study has been published in the Journal of Clinical Trials showing both Safety Effectiveness.

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SUNEKOS® 200 & 1200


Sunekos® 200


Sunekos® 200 is the first line product and it is suitable for all types of dermis.

Sunekos® 200 contains a low molecular weight Hyaluronic Acid.  It can be used alone to treat the face, neck, décolletage and hands and is great for younger people. It is also ideal for dark eye circles and eyebags.

The intradermal treatment with Sunekos® 200 corrects and protects the dermis from the signs of aging. It is the only natural product in professional dermo-aesthetics that stimulates the synthesis of collagen and elastin, restoring elasticity and volume to the skin. Other benefits include:

  • Superficial and deep hydration

  • Natural production of collagen, elastin & Type IV collagen in the dermis layer

  • Restore skin elasticity and natural volume

  • Reduction of facial volume loss

  • Reduce expression lines and thin wrinkles

  • Stimulation of fibroblast

Sunekos® 1200


Sunekos® 1200 is a booster with antioxidants properties that helps in treating severe wrinkles and damaged skin. In addition, it has a medium-high density of 1,200,000 Dalton of Hyaluronic acid, which brings more volume and protects fibroblasts and structural elements of the dermis as a free Radical "Scavenger". These antioxidants and volumising properties boosts the effects of Sunekos® 200.

Sunekos® 1200 is a medium molecular weight HA. It is ideal for skin hydrolifting, especially in matured, crepy saggy skin.

Having said so, in practice, both Sunekos® 1200 and Sunekos® 200 can be used in combination depending on the desired results. To get the best results from Sunekos®, it is recommended to combine the action of Sunekos® 200 and Sunekos® 1200 to create a “scaffold” through the “cushion” technique.




Profhilo is a Hybrid Complex made of H-HA and L-HA. This combination of hyaluronic acid’s different molecular weights gives a synergistic effect that benefits the skin. The high molecular weight HA protects the skin’s integrity and ability to retain moisture while the low molecular weight HA hydrates the skin with is hydrophilic properties.

Known as 逆針 or “Time Reversing ”, Profhilo is the latest multi-purpose injectable treatment for skin rejuvenation, hydration and collagen stimulation. It is a skin injectable treatment that delivers hyaluronic acid to all the layers of the skin.


Although Profhilo’s main ingredient is similar to that of fillers and skinboosters, the hyaluronic acid in Profhilo is significantly different in both concentration and structure. It currently has the highest concentration of Hyaluronic Acid (HA) among other skin boosters.

Profhilo also stimulates tissue Bio-remodelling, and significant improvements in elastin and collagen can be seen.

Profhilo is suitable for anyone who is looking to improve their skin. It works especially well for anyone with signs of ageing skin looking to hydrate, tighten, and improve the skin quality as it promotes collagen and elastin growth to reduce skin laxity and improve skin hydration. It is most effective for mild to moderate cases of skin laxity and fine lines.


There is usually no downtime after treatment with Profhilo® and patients can typically resume their daily activities immediately after the treatment.


Patients only need to attend a second follow-up session a month after the initial treatment.




NucleoFILL is an innovative treatment that, using the beneficial properties of polynucleotides, works on three levels, stimulating the skin to rebuild. It is a preparation for deep renewal and Bio-stimulation of the skin, developed on the basis of natural polynucleotides.

Bio-stimulation of the skin consists in stimulating its own regenerative capabilities – skin renewal occurs thanks to the occurrence of natural processes.

Polynucleotides are small fragments of DNA and RNA nucleic acids, found in all organisms. They are entirely bio-compatabilable with the human body. Polynucleotides have the ability to spatially attach a large number of water molecules, increasing tissue hydration, they also affect the increase in the number and activity of fibroblasts, i.e. the most important cells responsible for the continuous restoration of many skin components.

NucleoFILL stimulates the production of elastin and collagen based on 3 Bio-revitalising principles – lifting, antioxidising and hydration. It is for all skin types and ages, but it’s especially good for dry skin, skin that’s been exposed to oxidative stress, or skin that’s showing signs of ageing.

In the case of products that are Bio-stimulants, the effect intensifies over time and the therapy requires a series of treatments. ​The treatment stimulates fibroblasts to create collagen and elastin; it also stimulates hydration and also has an antioxidant effect.


In addition, they also play an important role in combating free radicals and inhibit photoaging, effectively protecting the skin against sun exposure.



How is SUNEKOS® Different from Other  HA Fillers?

Unlike most dermal fillers that only incorporate hyaluronic acids that physically plump up the skin, SUNEKOS® incorporates a specific and precise mix of six amino acids (HY6AA): Glycine, L-Proline. L- Alanine, L-Leucine, L-Lysine and L-Valine. This patented amino acid combination has been proven to restore the health and elasticity of the skin. The hyaluronic acid works as a carrier for the amino acids to bring them to the right layer of the skin; in this way, it targets the ECM where collagen, elastin and fibroblast activities take place and creates a more natural result by communicating with the skin on an intercellular level so that it can heal and mend itself. For this reason, the injectable can be used on multiple areas including the hands, face , chest, hands, lips and delicate eye area, as well as the loose skin around the neck.


In terms of skin quality improvement, SUNEKOS® is superior. This is due to its mechanism of action. SUNEKOS® produces more natural skin quality repair and healing results, boosting collagen and elastin in the skin, aiding softening of eyebags and reducing dark eye circles. Fillers such as RD2 can improve dark eye circles but not eyebags as it fills up the volume deficit. However, in terms of how fast results are achieved, fillers would be superior, giving faster results as it’s a direct filling effect vs skin quality boosting which takes time.

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In comparison to SUNEKOS®, PROFHILO is a hyaluronic acid gel product, unlike SUNEKOS®, which comes in the form of liquids (amino acids and hyaluronic acid).


Both SUNEKOS® and PROFHILO are effective in treating skins which have lost elasticity and firmness due to ageing. 


PROFHILO acts as a hydrator rather than a filler. This makes it fantastic for those with tired, dull-looking skin, transforming it into firm and luminous skin. It provides a lifting effect by boosting the volume of the treated areas and restores the overall integrity of the skin, but it does not improve skin texture. This effect takes place within 3-5 days of treatment. Over the next few weeks collagen and elastin production is stimulated, producing a secondary effect of skin tightening. PROFHILO is generally suited for individuals who are experiencing slight signs of skin ageing, and the treatment can only be applied on the lower and the neck.


SUNEKOS® works by stimulating the fibroblasts in the skin to encourage it to produce a complete mix of collagen and elastin, restoring the vibrancy, youthful glow and health of the skin. It helps to achieve the desirable volumising effect on the treated areas, reduce the appearance of fine lines and wrinkles, and further deeply hydrate the dermis layer. Thus, resulting in a plump and more youthful visage. It is often better suited to patients with skin displaying advanced signs of ageing such as severe wrinkles, sun-damaged and crepey skin because, alongside hydrating Hyaluronic acid, the formulation also contains powerful amino acid proteins that help to strengthen and firm the skin it is also helps to improve the condition of other skin problems including; lack of hydration, acne scarring, dark circles under eyes and sun damage.

The benefit of using SUNEKOS® is, it is the only natural product available in aesthetics that stimulates collagen and elastin, whilst restoring the elasticity and volume within the skin. SUNEKOS® is an ideal treatment option for patients who aren’t looking for fillers or BTX but would like to rejuvenate their complexion and maintain a natural look. In contrast, PROFHILO skin booster is ideal for a quick fix that works wonders with rejuvenating the skin look and feel. 


PROFHILO is not a filler. It is a patented technology of bio-remodeling injectable made of hyaluronic acid (HA), a potent moisturising factor naturally found in skin, muscle, and joints. Its ability to draw 1000 times its own weight in water into the skin makes it ideal for binding and retaining water molecules, hydrating the skin from within to leave it fresh and radiant. The treatment plumps the skin and diminishes fine lines and wrinkles whilst boosting the skin’s radiance and dewiness – delivering a long-lasting serum-type effect, but without the serum.

The effect of Profhilo is largely glow-giving. Richly hydrating the skin changes its light-reflecting properties, giving your complexion a radiance that no highlighter can match.

NUCLEOFILL is not a filler, but is a relatively new bio-stimulator (in the form of gel) for skin rejuvenation and protection. It consists of high molecular weight PDRN, derived from Salmon DNA.  It does the all-important job of stimulating fibroblasts – the major cells responsible for the production of collagen by stimulating directly onto the specific receptors on the fibroblast cells and produces the healthy collagen that we have in our youth.


As an anti-ageing treatment, it is designed to help cells retain water, improve skin elasticity and tightness, and aid in the prevention of wrinkles.  It also offers various products for specific concerns and, as well as skin regeneration, there are also options for the neck, eyes, and even the scalp to stimulate hair growth.

NUCLEOFILL is fantastic for the more mature age group as it regenerates sagging and dehydrated skin and thickens the tissues. It is used for patients who are concerned with fine lines and wrinkles and loss of elasticity on the face or neck. It treats various indications, making it a good option for under-eye crepiness, wrinkles, and hollows. We can combine these treatments if desired, or use just the one.

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